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新生儿葡萄球菌脓皮病的流行病学与防控:对一种使用4%氯己定洗涤剂溶液进行常规脐带护理方法的评估

Epidemiology and control of staphylococcal pyoderma among newborn infants: evaluation of a method for routine cord care with 4 per cent chlorhexidine-detergent solution.

作者信息

Seeberg S, Brinkhoff B

出版信息

J Hosp Infect. 1984 Jun;5(2):121-36. doi: 10.1016/0195-6701(84)90116-6.

Abstract

The incidence and types of staphylococcal purulent lesions were prospectively studied among 3602 newborn infants. During an epidemic of post-discharge pyoderma, 87 per cent of all Staphylococcus aureus isolates from lesions could be traced to the nursery. The risk of post-discharge disease was related to the degree of staphylococcal skin colonization in the nursery. A method for routine cord care in the nursery with 4 per cent chlorhexidine-detergent solution was evaluated and proved to be effective in reducing staphylococcal colonization in the nursery as well as purulent skin disease at home. The clinical effectiveness of the regimen was followed up for 19 months and a persistent low infection rate was obtained among infants in the post-discharge period.

摘要

对3602名新生儿的葡萄球菌化脓性损伤的发病率和类型进行了前瞻性研究。在出院后脓皮病流行期间,从损伤部位分离出的所有金黄色葡萄球菌中有87%可追溯到托儿所。出院后患病的风险与托儿所中葡萄球菌皮肤定植的程度有关。对托儿所中用4%洗必泰洗涤剂溶液进行常规脐带护理的方法进行了评估,结果证明该方法在减少托儿所中的葡萄球菌定植以及家中的化脓性皮肤病方面是有效的。对该方案的临床效果进行了19个月的随访,出院后时期的婴儿中感染率持续较低。

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