Verber I G, Pagan F S
Department of Paediatrics, Memorial Hospital, Darlington.
Arch Dis Child. 1993 May;68(5 Spec No):594-6. doi: 10.1136/adc.68.5_spec_no.594.
The use of antiseptic treatment during cord care varies from unit to unit. Although it may reduce bacterial colonisation it may also delay cord separation. Where antiseptic treatment is used there is uncertainty as to the best agent. Hexachlorophane powder (0.3%) and 4% chlorhexidene detergent were each compared with dry cord care as a control on a two ward maternity unit in a six month open study. Of 133 infants treated with hexachlorophane 44 (33%) became heavily colonised with Staphylococcus aureus compared with 80 (47%) of 171 controls; a reduction of one third. Chlorhexidene reduced colonisation by more than half; 17 (16%) of 104 compared with 41 (42%) of 98 controls. Chlorhexidene was associated with cord attachment at 10 days in 29 (28%) infants compared with 31 of 515 (6%) infants when it was not used. Hexachlorophane was more acceptable to the nursing staff. The reduction in colonisation with the two compounds was largely due to the suppression of cross infection.
在脐带护理过程中,抗菌治疗的使用在不同科室存在差异。尽管它可能会减少细菌定植,但也可能会延迟脐带脱落。在使用抗菌治疗时,对于最佳药物尚无定论。在一项为期六个月的开放性研究中,在一个有两个病房的产科单位,将六氯酚粉末(0.3%)和4%洗必泰洗涤剂分别与作为对照的干性脐带护理进行了比较。在133例接受六氯酚治疗的婴儿中,44例(33%)被金黄色葡萄球菌严重定植,而171例对照中有80例(47%);减少了三分之一。洗必泰使定植减少了一半以上;104例中有17例(16%),而98例对照中有41例(42%)。在使用洗必泰的婴儿中,29例(28%)在10天时脐带仍未脱落,而未使用时515例婴儿中有31例(6%)出现这种情况。护理人员更喜欢六氯酚。这两种化合物使定植减少主要是由于交叉感染的抑制。