Alavi J B
Med Clin North Am. 1984 May;68(3):545-56. doi: 10.1016/s0025-7125(16)31115-4.
Current concepts of the pathophysiology of the sickling process are reviewed. New approaches to treatment - including induced hyponatremia, membrane-active antisickling agents, and gene manipulation - are described.
本文综述了镰状化过程病理生理学的当前概念。描述了新的治疗方法,包括诱导低钠血症、膜活性抗镰状化药物和基因操作。