Yoshida J, Kageyama N, Ueda R, Takahashi T
Neurosurg Rev. 1984;7(1):23-8. doi: 10.1007/BF01743287.
Tumour specific and various tumour-associated antigens expressed on human glioma cells were reported from many laboratories. These have been identified by xeno-, allo-, or auto-sera and more recently by utilizing monoclonal antibodies produced by hybridoma technique. In this article, the results of reports are summarized comparing the studies with conventional antisera and monoclonal antibodies. The present and future clinical applications of these monoclonal antibodies are described.
许多实验室报告了在人类胶质瘤细胞上表达的肿瘤特异性和各种肿瘤相关抗原。这些抗原已通过异种血清、同种血清或自身血清鉴定出来,最近还通过利用杂交瘤技术产生的单克隆抗体进行了鉴定。在本文中,总结了将这些研究与传统抗血清和单克隆抗体进行比较的报告结果。还描述了这些单克隆抗体目前和未来的临床应用。