[抗-I自身抗体与猪和猴红细胞的反应]
[Reaction of anti-I auto-antibodies with erythrocytes from the pig and monkey].
作者信息
Reviron M, Janvier D, Reviron J
出版信息
Rev Fr Transfus Immunohematol. 1984 Apr;27(2):155-67. doi: 10.1016/s0338-4535(84)80034-3.
Starting from 5 human sera containing anti-I cold autoagglutinins, it was possible, using adsorption/elution trials with pig's and rhesus monkey's RBC, to separate 8 anti-I antibodies because 3 of the initial sera were heterogeneous. Each of them had 2 anti-I different as regards the reactivity with the animal RBC and the anti-ID or the anti-IF reactivity. On the whole, among 8 separated fractions 1 reacted only on pig's RBC and had the characteristics of an anti-ID; 3 reacted only on rhesus monkey's RBC and were anti-IF; 4 had a cross-reactivity with pig's and monkey's RBC: 2 of them were anti-IF and 2 anti-ID. Anti-ID fixed preferably on pig's RBC and anti-IF on rhesus monkey's RBC but monkey's RBC are not entirely lacking in ID determinants and pig's RBC in IF determinants.
从5份含有抗-I冷凝集素的人血清开始，通过用猪和恒河猴的红细胞进行吸附/洗脱试验，有可能分离出8种抗-I抗体，因为最初的3份血清是异质的。它们中的每一份都有2种抗-I，在与动物红细胞的反应性以及抗-ID或抗-IF反应性方面有所不同。总体而言，在分离出的8个组分中，1个仅与猪红细胞反应，具有抗-ID的特征；3个仅与恒河猴红细胞反应，为抗-IF；4个与猪和猴的红细胞有交叉反应：其中2个是抗-IF，2个是抗-ID。抗-ID优先固定在猪红细胞上，抗-IF固定在恒河猴红细胞上，但猴红细胞并非完全缺乏ID决定簇，猪红细胞也并非完全缺乏IF决定簇。
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