Okuda M, Ishikawa T, Saito Y, Shimizu T, Baba S
Ann Allergy. 1984 Aug;53(2):178-85.
N-(3,4-dimethoxycinnamoyl) anthranilic acid (N-5'), a new orally useable mast cell stabilizer, was investigated for its efficacy, safety and usefulness in the treatment of 302 patients with perennial nasal allergy by an intergroup, double-blind comparative test using disodium cromoglycate (DSCG) and an inactive placebo as control. The results indicated that N-5', as a mild mast cell stabilizer, was comparable to DSCG in efficacy and minimum in side effect.
N-(3,4-二甲氧基肉桂酰)邻氨基苯甲酸(N-5')是一种新型的可口服的肥大细胞稳定剂,通过以色甘酸钠(DSCG)和无活性安慰剂作为对照的组间双盲对比试验,对302例常年性鼻过敏患者进行了其治疗效果、安全性和实用性的研究。结果表明,N-5'作为一种温和的肥大细胞稳定剂,在疗效上与色甘酸钠相当,且副作用最小。