• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

N - 5'用于常年性变应性鼻炎的临床评估——多诊所、组间、双盲对比法试验

A clinical evaluation of N-5' with perennial-type allergic rhinitis--a test by the multi-clinic, intergroup, double-blind comparative method.

作者信息

Okuda M, Ishikawa T, Saito Y, Shimizu T, Baba S

出版信息

Ann Allergy. 1984 Aug;53(2):178-85.

PMID:6205614
Abstract

N-(3,4-dimethoxycinnamoyl) anthranilic acid (N-5'), a new orally useable mast cell stabilizer, was investigated for its efficacy, safety and usefulness in the treatment of 302 patients with perennial nasal allergy by an intergroup, double-blind comparative test using disodium cromoglycate (DSCG) and an inactive placebo as control. The results indicated that N-5', as a mild mast cell stabilizer, was comparable to DSCG in efficacy and minimum in side effect.

摘要

N-(3,4-二甲氧基肉桂酰)邻氨基苯甲酸(N-5')是一种新型的可口服的肥大细胞稳定剂,通过以色甘酸钠(DSCG)和无活性安慰剂作为对照的组间双盲对比试验,对302例常年性鼻过敏患者进行了其治疗效果、安全性和实用性的研究。结果表明,N-5'作为一种温和的肥大细胞稳定剂,在疗效上与色甘酸钠相当,且副作用最小。

相似文献

1
A clinical evaluation of N-5' with perennial-type allergic rhinitis--a test by the multi-clinic, intergroup, double-blind comparative method.N - 5'用于常年性变应性鼻炎的临床评估——多诊所、组间、双盲对比法试验
Ann Allergy. 1984 Aug;53(2):178-85.
2
Treatment of chronic perennial allergic rhinitis: a double-blind trial of cromolyn sodium.慢性常年性变应性鼻炎的治疗:色甘酸钠双盲试验
Ann Allergy. 1977 Sep;39(3):169-74.
3
Clinical and histological study to assess changes in the nasal mucosa in patients with chronic perennial rhinitis comparing sodium cromoglycate and placebo.一项临床和组织学研究,旨在比较色甘酸钠和安慰剂对慢性常年性鼻炎患者鼻黏膜变化的影响。
Rhinology. 1978 Jun;16(2):89-95.
4
Clinical investigation of ketotifen in perennial allergic rhinitis: a double-blind comparative study of ketotifen and clemastine fumarate.酮替芬治疗常年性变应性鼻炎的临床研究:酮替芬与富马酸氯马斯汀的双盲对照研究
Rhinology. 1984 Sep;22(3):171-82.
5
Allergic perennial and non-allergic, vasomotor rhinitis treated with budesonide nasal spray.
Rhinology. 1980 Sep;18(3):135-42.
6
The effects of disodium cromoglycate (DSCG) and beclomethasone dipropionate (BDA) on the delayed nasal mucosa response to allergen challenge.色甘酸钠(DSCG)和二丙酸倍氯米松(BDA)对变应原激发后鼻黏膜迟发反应的影响。
Ann Allergy. 1984 Feb;52(2):111-24.
7
Rynacrom (sodium cromoglycate) in intractable perennial rhinitis.色甘酸钠(Rynacrom)治疗顽固性常年性鼻炎。
N Z Med J. 1975 Oct 22;82(550):265-6.
8
Efficacy double-blind, crossover study of sodium cromoglycate in patients with seasonal allergic rhinitis.色甘酸钠治疗季节性变应性鼻炎的双盲交叉疗效研究
Ann Allergy. 1977 Jan;38(1):42-45.
9
Disodium chromoglycate therapy in perennial rhinitis.色甘酸钠治疗常年性鼻炎。
Acta Otolaryngol Suppl. 1979;360:30-2. doi: 10.3109/00016487809123463.
10
Intranasal immunotherapy with Dermatophagoides extract: in vivo and in vitro results of a double-blind placebo-controlled trial.用尘螨提取物进行鼻内免疫疗法:一项双盲安慰剂对照试验的体内和体外结果
Rhinology. 1995 Sep;33(3):126-31.

引用本文的文献

1
Therapeutic Effects of Long-Term Administration of Tranilast in an Animal Model for the Treatment of Fibroids.曲尼司特长期给药治疗子宫肌瘤动物模型的疗效。
Int J Mol Sci. 2023 Jun 21;24(13):10465. doi: 10.3390/ijms241310465.
2
Biological Activities, Health Benefits, and Therapeutic Properties of Avenanthramides: From Skin Protection to Prevention and Treatment of Cerebrovascular Diseases.燕麦酰胺的生物学活性、健康益处和治疗特性:从皮肤保护到预防和治疗脑血管疾病。
Oxid Med Cell Longev. 2018 Aug 23;2018:6015351. doi: 10.1155/2018/6015351. eCollection 2018.
3
Tranilast Blocks the Interaction between the Protein S100A11 and Receptor for Advanced Glycation End Products (RAGE) V Domain and Inhibits Cell Proliferation.
曲尼司特阻断蛋白质S100A11与晚期糖基化终产物受体(RAGE)V结构域之间的相互作用并抑制细胞增殖。
J Biol Chem. 2016 Jul 1;291(27):14300-14310. doi: 10.1074/jbc.M116.722215. Epub 2016 May 12.
4
House dust mite avoidance measures for perennial allergic rhinitis.针对常年性变应性鼻炎的尘螨回避措施。
Cochrane Database Syst Rev. 2010 Jul 7;2010(7):CD001563. doi: 10.1002/14651858.CD001563.pub3.
5
House dust mite avoidance measures for perennial allergic rhinitis: a systematic review of efficacy.常年性变应性鼻炎的屋尘螨规避措施:疗效的系统评价
Br J Gen Pract. 2003 Apr;53(489):318-22.
6
Grading the severity of allergic rhinitis for treatment strategy and drug study purposes.为治疗策略和药物研究目的对过敏性鼻炎的严重程度进行分级。
Curr Allergy Asthma Rep. 2001 May;1(3):235-41. doi: 10.1007/s11882-001-0010-x.
7
Ciliary activity in patients with nasal allergies.
Arch Otorhinolaryngol. 1985;242(2):141-7. doi: 10.1007/BF00454413.