色甘酸钠治疗季节性变应性鼻炎的双盲交叉疗效研究
Efficacy double-blind, crossover study of sodium cromoglycate in patients with seasonal allergic rhinitis.
作者信息
Nizami R M, Baboo M T
出版信息
Ann Allergy. 1977 Jan;38(1):42-45.
PMID:402093
Abstract
In a double-blind, crossover, placebo-controlled study, consisting of 100 clinical trials, the active drug (sodium cromoglycate) was effective in 83.2%, while in 11.6% the placebo was judged more effective (p less than 0.0001). Four patients suffered minor side effects. No deleterious effect on the nasal mucosa was noticed and no one complained that the drug produced sedation.
摘要
在一项由100项临床试验组成的双盲、交叉、安慰剂对照研究中，活性药物（色甘酸钠）的有效率为83.2%，而11.6%的患者认为安慰剂更有效（p<0.0001）。4名患者出现轻微副作用。未观察到对鼻黏膜有有害影响，也没有人抱怨该药物会引起镇静作用。
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