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动脉手术中的生物移植——长期结果(一、同种静脉——二、改良异种牛颈动脉——三、人脐静脉)

Biogenic grafts in arterial surgery--long-term results (I. The homologous vein--II. The modified heterologous bovine carotid artery--III. The human umbilical vein).

作者信息

Sciacca V, Walter G, Becker H M

出版信息

Thorac Cardiovasc Surg. 1984 Jun;32(3):157-64. doi: 10.1055/s-2007-1023374.

Abstract

This report summarizes the authors' experience with homologous vein grafts, modified heterologous bovine carotid artery grafts and human umbilical vein grafts in reconstructive vascular surgery. The homologous saphenous vein, taken from living donors, was implanted in 21 patients. The high percentage of early and late complications (28% and 38%, respectively), the difficult availability and the development of modern materials appear to suggest that these grafts, at least the type used in this study, should no longer be employed. The experience with 102 femoro-popliteal and femoro-tibial bypasses in 140 revascularization operations carried out with modified heterologous bovine carotid artery grafts (Solcograft) is presented. The cumulative patency rate was 43% after 5 years for the above-knee and 33% for the below-knee femoro-popliteal bypasses. The high early and late complication rates (37% and 35%) lead us to believe that this graft should also no longer be employed. The human umbilical cord vein (Meadox-Dardik-Biograft) was used in performing 68 femoro-popliteal and 15 femoro-crural bypasses in 60 limbs of 57 patients. The patency rates calculated according to the standard life table method was 36% for the above-knee (after 5 years) and 32% for the below-knee femoro-popliteal bypass (after 4 years) and 31% (after 3 years) for the femoro-tibial bypass, respectively. On the understanding that other materials should be preferred in the individual case, this material still seems to be recommendable as a graft of second or third choice.

摘要

本报告总结了作者在重建性血管外科手术中使用同种异体静脉移植物、改良异种牛颈动脉移植物和人脐静脉移植物的经验。取自活体供体的同种异体大隐静脉植入了21例患者。早期和晚期并发症的高发生率(分别为28%和38%)、获取困难以及现代材料的发展似乎表明,这些移植物,至少是本研究中使用的类型,不应再被采用。文中介绍了使用改良异种牛颈动脉移植物(Solcograft)在140例血管重建手术中进行102例股腘和股胫旁路移植的经验。对于膝上股腘旁路移植,5年后的累积通畅率为43%,膝下为33%。早期和晚期并发症的高发生率(37%和35%)使我们认为这种移植物也不应再被采用。人脐带静脉(Meadox-Dardik-Biograft)用于57例患者的60条肢体进行68例股腘和15例股胫旁路移植。根据标准寿命表法计算,膝上(5年后)股腘旁路移植的通畅率为36%,膝下为32%(4年后),股胫旁路移植为31%(3年后)。尽管了解到在个别情况下应优先选择其他材料,但这种材料似乎仍可作为第二或第三选择的移植物推荐使用。

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