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[滑膜切除术对关节软骨中糖胺聚糖含量的影响]

[Effect of synovectomy on the glycosaminoglycan content in the articular cartilage].

作者信息

Reichel W

出版信息

Z Orthop Ihre Grenzgeb. 1984 May-Jun;122(3):335-40. doi: 10.1055/s-2008-1044636.

DOI:10.1055/s-2008-1044636
PMID:6206662
Abstract

Experimental Synovectomy of canine-knee was used for the study of synovial regeneration; histochemical staining with safranin-O and alcian-blue 8 GS, scanning electronmicroscopical studies of cryostat sections with sulfur Stimulation and biochemical analysis of the acid glycosaminoglycan content of cartilage were performed. Following synovectomy the developed "neosynovialis" shows contrary to the situation before a remarkable fibrosis beneath the lining-cells. The acid glycosaminoglycan-content of the cartilage early drops down; 50 days later the GAG-content reaches nearly normal values. At this time not only the histological appearance, but also the nutritive function of neosynovialis seems to be sufficient.

摘要

采用犬膝关节实验性滑膜切除来研究滑膜再生;进行了番红O和阿尔辛蓝8GS组织化学染色、硫刺激的低温切片扫描电子显微镜研究以及软骨酸性糖胺聚糖含量的生化分析。滑膜切除后,形成的“新滑膜”与之前的情况相反,在衬里细胞下方出现明显纤维化。软骨的酸性糖胺聚糖含量早期下降;50天后,糖胺聚糖含量几乎达到正常值。此时,不仅新滑膜的组织学外观,而且其营养功能似乎都足够。

相似文献

1
[Effect of synovectomy on the glycosaminoglycan content in the articular cartilage].[滑膜切除术对关节软骨中糖胺聚糖含量的影响]
Z Orthop Ihre Grenzgeb. 1984 May-Jun;122(3):335-40. doi: 10.1055/s-2008-1044636.
2
The effect of synovectomy on the articular cartilage of the knee joint in rabbits.滑膜切除术对兔膝关节软骨的影响。
Int Orthop. 1985;8(4):247-53. doi: 10.1007/BF00266868.
3
The effect of synovectomy on articular cartilage.滑膜切除术对关节软骨的影响。
J Bone Joint Surg Am. 1967 Sep;49(6):1099-108.
4
Enzyme activity in articular cartilage after synovectomy of the knee in the rabbit.兔膝关节滑膜切除术后关节软骨中的酶活性
J Bone Joint Surg Br. 1972 May;54(2):360-70.
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Synovial regeneration and articular cartilage changes after synovectomy in normal and steroid-treated rabbits.正常及经类固醇处理的兔子滑膜切除术后的滑膜再生及关节软骨变化
J Bone Joint Surg Br. 1975 Nov;57(4):454-62.
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Influence of Knee Immobilization on Chondrocyte Apoptosis and Histological Features of the Anterior Cruciate Ligament Insertion and Articular Cartilage in Rabbits.膝关节固定对兔前交叉韧带止点及关节软骨软骨细胞凋亡和组织学特征的影响
Int J Mol Sci. 2017 Jan 26;18(2):253. doi: 10.3390/ijms18020253.
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The effect of synovectomy on synovium and cartilage in early rheumatoid arthritis.滑膜切除术对早期类风湿性关节炎患者滑膜及软骨的影响。
Orthop Clin North Am. 1973 Oct;4(4):1057-84.
8
Radiation synovectomy stimulates glycosaminoglycan synthesis by normal articular cartilage.放射性滑膜切除术可刺激正常关节软骨合成糖胺聚糖。
J Lab Clin Med. 1989 Jul;114(1):27-35.
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Long-distance running causes site-dependent decrease of cartilage glycosaminoglycan content in the knee joints of beagle dogs.长跑导致比格犬膝关节软骨糖胺聚糖含量出现部位依赖性降低。
Arthritis Rheum. 1993 Oct;36(10):1451-9. doi: 10.1002/art.1780361018.
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In vivo studies of articular tissue damage mediated by catabolin/interleukin 1.关于分解代谢素/白细胞介素1介导的关节组织损伤的体内研究。
Ann Rheum Dis. 1987 Jul;46(7):527-33. doi: 10.1136/ard.46.7.527.

引用本文的文献

1
The stabilizing effect of synovectomy on the synovial membrane in arthritic rabbit knees.滑膜切除术对兔膝关节炎滑膜的稳定作用。
Arch Orthop Trauma Surg (1978). 1986;105(1):11-7. doi: 10.1007/BF00625653.
2
[Technic of synovectomy in the infected knee joint].[感染性膝关节滑膜切除术的技术]
Unfallchirurgie. 1987 Oct;13(5):260-2. doi: 10.1007/BF02588506.