Okunewick J P, Braunschweiger P G
Experientia. 1978 Jan 15;34(1):108-9. doi: 10.1007/BF01921932.
Evidence is presented that during viral leukemogenesis spleen cell nuclei show an increase in labelling index and mean grain count, that is not accompanied by any changes in the nuclear level of DNA-polymerase-alpha. It is suggested that polymerase production remains under the control of the normal cell mechanisms and the virus may affect cell proliferation by altering the primer-template levels.
有证据表明，在病毒性白血病发生过程中，脾细胞核的标记指数和平均颗粒计数增加，而DNA聚合酶α的核水平没有任何变化。有人提出，聚合酶的产生仍受正常细胞机制的控制，病毒可能通过改变引物-模板水平来影响细胞增殖。
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