Somberg J C
J Clin Pharmacol. 1984 Jul;24(7):320-7. doi: 10.1002/j.1552-4604.1984.tb01841.x.
Sudden cardiac death is a major problem in the United States. Our goal is to identify high-risk patients and to be able to target antiarrhythmic therapy to this population. Ambulatory electrocardiography, exercise tolerance testing, and programmed electrical stimulation studies may aid in the identification of patients at risk for sudden cardiac death and the selection of antiarrhythmic therapy. Each technique has its advantages, disadvantages, and limitations. These considerations must be taken into account if the procedure is to be optimally employed. We are in a period of rapid development of new antiarrhythmic agents. It is essential to fully understand the techniques employed to evaluate antiarrhythmic therapy.
心脏性猝死在美国是一个重大问题。我们的目标是识别高危患者,并能够针对这一人群进行抗心律失常治疗。动态心电图、运动耐量测试和程控电刺激研究可能有助于识别有心脏性猝死风险的患者以及选择抗心律失常治疗方法。每种技术都有其优点、缺点和局限性。如果要最佳地应用该程序,就必须考虑这些因素。我们正处于新型抗心律失常药物快速发展的时期。充分了解用于评估抗心律失常治疗的技术至关重要。