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体内子宫细胞雌激素结合的动力学

Dynamics of estrogen binding by uterine cells in vivo.

作者信息

Tchernitchin A, Tchernitchin X, Collao C, Rodríguez A

出版信息

Experientia. 1978 Jan 15;34(1):134-6. doi: 10.1007/BF01921947.

DOI:10.1007/BF01921947
PMID:620726
Abstract

The dynamics of the in vivo binding and release of tritiated estradiol in different uterine cell types are described. The very early binding of estrogens by the cytosol-nuclear and the eosinophil receptor systems is in accordance with the hypothesis that some estrogenic effects are mediated by these receptor systems.

摘要

描述了氚标记雌二醇在不同子宫细胞类型中的体内结合和释放动态。雌激素通过胞质溶胶-细胞核和嗜酸性粒细胞受体系统的早期结合与某些雌激素效应由这些受体系统介导的假说相符。

相似文献

1
Dynamics of estrogen binding by uterine cells in vivo.体内子宫细胞雌激素结合的动力学
Experientia. 1978 Jan 15;34(1):134-6. doi: 10.1007/BF01921947.
2
Differential response of individual uterine cell types from immature rats treated with estradiol.用雌二醇处理的未成熟大鼠的单个子宫细胞类型的差异反应。
Endocrinology. 1980 May;106(5):1634-49. doi: 10.1210/endo-106-5-1634.
3
Androgen-uterine interaction: nuclear translocation of the estrogen receptor and induction of the synthesis of the uterine-induced protein (IP) by high concentrations of androgens in vitro but not in vivo.雄激素与子宫的相互作用：雌激素受体的核转位以及高浓度雄激素在体外而非体内诱导子宫诱导蛋白（IP）的合成。
Endocrinology. 1976 Mar;98(3):702-16. doi: 10.1210/endo-98-3-702.
4
Nuclear binding of the estrogen receptor: heterogeneity of sites and uterotropic response.雌激素受体的核结合：位点的异质性与促子宫生长反应
Adv Exp Med Biol. 1979;117:17-46. doi: 10.1007/978-1-4757-6589-2_2.
5
Estrogenic activity of the insecticide chlordecone (Kepone) and interaction with uterine estrogen receptors.杀虫剂开蓬（十氯酮）的雌激素活性及其与子宫雌激素受体的相互作用。
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6641-5. doi: 10.1073/pnas.76.12.6641.
6
Different nuclear binding sites for antiestrogen and estrogen receptor complexes.抗雌激素与雌激素受体复合物的不同核结合位点。
Endocrinology. 1977 Feb;100(2):420-6. doi: 10.1210/endo-100-2-420.
7
Estrogenic effects of the antiprogestin onapristone (ZK98.299) in the rodent uterus.抗孕激素奥那司酮（ZK98.299）对啮齿动物子宫的雌激素样作用。
Am J Obstet Gynecol. 1994 Jul;171(1):188-94. doi: 10.1016/0002-9378(94)90468-5.
8
Characterization of the estrogen receptors in the uterine and blood eosinophil leukocytes.子宫和血液嗜酸性粒细胞中雌激素受体的特征分析。
Experientia. 1976 Oct 15;32(10):1240-2. doi: 10.1007/BF01953070.
9
Cellular variations in estrogen receptor mRNA translation in the developing brain: evidence from combined [125I]estrogen autoradiography and non-isotopic in situ hybridization histochemistry.发育中大脑雌激素受体mRNA翻译的细胞变化：来自[125I]雌激素放射自显影与非同位素原位杂交组织化学联合研究的证据。
Brain Res. 1992 Mar 27;576(1):25-41. doi: 10.1016/0006-8993(92)90606-a.
10
Actions and interactions of delta 5-androstene-3 beta, 17 beta-diol and 17 beta-estradiol in the immature rat uterus.δ5-雄烯-3β,17β-二醇与17β-雌二醇在未成熟大鼠子宫中的作用及相互作用
Endocrinology. 1981 Apr;108(4):1587-93. doi: 10.1210/endo-108-4-1587.

引用本文的文献

1
Uterine epithelial and eosinophil estrogen receptors in rats during the estrous cycle.大鼠发情周期中子宫上皮细胞和嗜酸性粒细胞雌激素受体
Histochemistry. 1982;74(4):443-52. doi: 10.1007/BF00496657.

本文引用的文献

1
RIBONUCLEIC ACID SYNTHESIS IN THE RAT UTERUS AND ITS EARLY RESPONSE TO ESTROGEN.大鼠子宫中的核糖核酸合成及其对雌激素的早期反应。
Arch Biochem Biophys. 1965 May;110:284-90. doi: 10.1016/0003-9861(65)90120-7.
2
Use of anhydrous vapors in post-fixation and in staining of reactive groups of proteins in frozen-dried specimens for electron microscopic studies.
Anat Rec. 1960 Dec;138:445-59. doi: 10.1002/ar.1091380405.
3
Submicroscopic structure of frozen-dried liver specifically stained for electron microscopy.经电子显微镜特殊染色的冻干肝脏的亚微观结构。
Anat Rec. 1957 May;128(1):91-111. doi: 10.1002/ar.1091280109.
4
The preparation of frozen-dried tissue for electron microscopy.用于电子显微镜检查的冻干组织的制备。
J Biophys Biochem Cytol. 1956 Jul 25;2(4 Suppl):37-43. doi: 10.1083/jcb.2.4.37.
5
High resolution autoradiography with dry mounted, freeze-dried frozen sections. Comparative study of six methods using two diffusible compounds 3H-estradiol and 3H-mesobilirubinogen.使用干裱、冻干冷冻切片的高分辨率放射自显影术。使用两种可扩散化合物3H-雌二醇和3H-中胆红素原对六种方法的比较研究。
J Histochem Cytochem. 1966 Mar;14(3):274-87. doi: 10.1177/14.3.274.
6
Radioautographic study of the effect of estradiol-17 , estrone, estriol, progesterone, testosterone and corticosterone on the in vitro uptake of 2,4,6,7- 3 H estradiol-17 by uterine eosinophils of the rat.关于雌二醇 -17β、雌酮、雌三醇、孕酮、睾酮和皮质酮对大鼠子宫嗜酸性粒细胞体外摄取 2,4,6,7-³H 雌二醇 -17β影响的放射自显影研究。
Steroids. 1972 Apr;19(4):575-86. doi: 10.1016/s0039-128x(72)80023-0.
7
Mechanism of action of the female sex hormones.女性性激素的作用机制。
Annu Rev Biochem. 1972;41:203-30. doi: 10.1146/annurev.bi.41.070172.001223.
8
Dramatic early increase in uterine eosinophils after oestrogen administration.
Nature. 1974 Mar 8;248(5444):142-3. doi: 10.1038/248142a0.
9
Fine structure of rat uterine eosinophils and the possible role of eosinophils in the mechanism of estrogen action.大鼠子宫嗜酸性粒细胞的精细结构以及嗜酸性粒细胞在雌激素作用机制中的可能作用。
J Steroid Biochem. 1973 May;4(3):277-82. doi: 10.1016/0022-4731(73)90051-4.
10
Adenosine 3',5'-monophosphate in rat uterus: acute elevation by estrogen.大鼠子宫中的3',5'-环磷酸腺苷：雌激素引起的急性升高。
Proc Natl Acad Sci U S A. 1967 Oct;58(4):1711-8. doi: 10.1073/pnas.58.4.1711.