Nozaki M, Mitsuhashi N, Takahashi I, Niibe H, Honma M
Gan No Rinsho. 1984 Aug;30(10):1314-20.
This is a clinical and pathological study of malignant germ tumors in the lung or mediastinum. Germ cell tumors may be considered to originate from primitive germ cells with totipotency. One of 3 cases showed clinical and pathological findings suggesting that a part of the tumor differentiated into many kinds of tissue, such as growing and metastasizing. Initial diagnosis was performed radiographically and pathologically with difficulty. But finally, the first patient was diagnosed as malignant teratoma, the second as yolk sac tumor and the third as choriocarcinoma, in consideration of the tumor markers and clinical process.
这是一项关于肺或纵隔恶性生殖细胞肿瘤的临床与病理研究。生殖细胞肿瘤可被认为起源于具有全能性的原始生殖细胞。3例病例中的1例显示出临床和病理表现，提示肿瘤的一部分分化为多种组织，如生长和转移。最初的诊断在影像学和病理学上都存在困难。但最终，考虑到肿瘤标志物和临床过程，第一例患者被诊断为恶性畸胎瘤，第二例为卵黄囊瘤，第三例为绒毛膜癌。
