Golenhofen K, Hannappel J
Experientia. 1978 Jan 15;34(1):64-5. doi: 10.1007/BF01921904.
In isolated muscle strips of porcine renal pelvis and ureter, the calcium antagonist nifedipine (3.10(-7) moles/l) completely suppressed spontaneous phasic mechanical activity and the phasic components of an adrenaline-induced activation (P-component). In the presence of nifedipine, adrenaline induced in pelvis preparations (but not in the ureter) a tonic contraction (T-component) which was on average 61% of the control reaction (SD +/- 26%; n = 35).
在猪肾盂和输尿管的离体肌肉条中,钙拮抗剂硝苯地平(3×10⁻⁷摩尔/升)完全抑制了自发性相性机械活动以及肾上腺素诱导激活的相性成分(P成分)。在硝苯地平存在的情况下,肾上腺素在肾盂制剂中(但不在输尿管中)诱导出强直性收缩(T成分),其平均为对照反应的61%(标准差±26%;n = 35)。