Vergnaud O, Maraud R
Biol Cell. 1984;51(1):97-104. doi: 10.1111/j.1768-322x.1984.tb00287.x.
The mesonephros of the chick embryo normally begins to regress during the second half of embryonic life. Experimental methods, such as adenohypophysis grafting, hypophysectomy or use of antithyroid drugs, which stimulate or depress the thyroid function of the embryo, modified accordingly the regressive processes occurring in the mesonephric Malpighian corpuscles, particularly at the level of the glomerular basement laminae. These results as well as the known sensitivity of the mesonephros to thyroxine and the concordance between the steps of embryonic thyroid development and the mesonephric modifications show that the thyroid normally plays a major determining role in this phenomenon.
鸡胚的中肾通常在胚胎发育后半期开始退化。诸如腺垂体移植、垂体切除或使用抗甲状腺药物等实验方法，这些方法刺激或抑制胚胎的甲状腺功能，相应地改变了中肾马尔皮基小体中发生的退化过程，特别是在肾小球基底膜水平。这些结果以及已知的中肾对甲状腺素的敏感性，以及胚胎甲状腺发育步骤与中肾变化之间的一致性表明，甲状腺通常在这一现象中起主要的决定性作用。
