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[肾上腺素对大鼠心房和心室变时性的影响]

[Effect of adrenaline on rat atrial and ventricular chronoinotropy].

作者信息

Gorbachev V V, Izakov V Ia

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1978 Jan;64(1):49-54.

PMID:620858
Abstract

The atria and ventricles were shown to differ from each other in: temporal course of contractions, relations between the strength of contractions and the interstimuli interval, resting potentiation, transitional processes after intermissions, character of response to adrenaline. For the first time the adrenaline was shown to annihilate differences in restitution processes occurring in atria and ventricles. The differences of responses in atria and ventricles seem to be due to concentration of endogenous catecholamines which modulate the electromechanical coupling of the rhythmically working myocardium.

摘要

研究表明,心房和心室在以下方面存在差异:收缩的时间进程、收缩强度与刺激间期之间的关系、静息期增强、间歇后的过渡过程、对肾上腺素的反应特性。首次发现肾上腺素可消除心房和心室在恢复过程中出现的差异。心房和心室反应的差异似乎是由于内源性儿茶酚胺的浓度不同,内源性儿茶酚胺可调节有节律工作的心肌的机电耦联。

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