利用单克隆抗体对派杰样网状细胞增生症中皮肤浸润细胞进行表型特征分析。

Phenotypic characterization of skin-infiltrating cells in pagetoid reticulosis by monoclonal antibodies.

作者信息

Gonzalez M, Martin-Pascual M, San Miguel J, Caballero M D, López Borrasca A

出版信息

Acta Derm Venereol. 1984;64(5):421-4.

Abstract

The immunological characterization of the infiltrating cells in a patient with a disseminated form of Pagetoid reticulosis (PR) was carried out-in histological section and cell suspensions--by means of a panel of monoclonal antibodies and classical markers (E-rosette and surface immunoglobulins (SIg]. Most of the infiltrating cells were seen to be mature T-lymphocytes with a suppressor/cytotoxic phenotype (T11+, T3+, T8+, T4-). The results suggest that this variant of PR represents a special histological type of cutaneous T cell lymphoma.

摘要

通过一组单克隆抗体和经典标志物（E花环和表面免疫球蛋白（SIg）），在组织学切片和细胞悬液中对一名播散型佩吉特样网状细胞增生症（PR）患者的浸润细胞进行了免疫学特征分析。可见大多数浸润细胞是具有抑制/细胞毒性表型的成熟T淋巴细胞（T11 +、T3 +、T8 +、T4 -）。结果表明，这种PR变体代表了皮肤T细胞淋巴瘤的一种特殊组织学类型。

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Phenotypic characterization of skin-infiltrating cells in pagetoid reticulosis by monoclonal antibodies.利用单克隆抗体对派杰样网状细胞增生症中皮肤浸润细胞进行表型特征分析。

Acta Derm Venereol. 1984;64(5):421-4.

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