van Voorst Vader P C, van Oostveen F, Houthoff H J, Marrink J
Acta Derm Venereol. 1984;64(5):430-2.
A patient with longstanding erythroderma and decreased sweat secretion due to the classical adult form of pityriasis rubra pilaris is described. The patient did not respond to oral megadoses of Vitamin A, even though a large increase of liver content of Vitamin A was demonstrated. Retinol-binding protein levels in serum of this patient and his relatives were normal. Danazol (Danatrol, Winthrop) therapy caused an increase of retinol-binding protein level, but clinical improvement did not occur.
描述了一名患有长期红皮病且因典型成人型毛发红糠疹导致汗液分泌减少的患者。尽管已证明该患者肝脏中维生素A含量大幅增加，但口服大剂量维生素A对其并无效果。该患者及其亲属血清中的视黄醇结合蛋白水平正常。达那唑（Danatrol，温思罗普公司生产）治疗使视黄醇结合蛋白水平升高，但未出现临床改善。
