Pierard G E, Pierard-Franchimont C
Am J Dermatopathol. 1984 Aug;6(4):397-410. doi: 10.1097/00000372-198408000-00015.
Photochemotherapy induces alterations in the skin that resemble those in xeroderma pigmentosum. Acute responses may be distinguished from late, chronic, and delayed responses to PUVA. All of the types of cells present in the skin are affected by photochemotherapy. The structure of the epidermis and of the superficial dermis are altered and, possibly as a consequence, neoplasms may ensue.
光化学疗法会引起皮肤改变,类似于着色性干皮病的皮肤改变。急性反应可与对补骨脂素加紫外线A疗法(PUVA)的晚期、慢性和延迟反应相区分。皮肤中存在的所有细胞类型都会受到光化学疗法的影响。表皮和浅表真皮的结构会发生改变,可能因此会引发肿瘤。