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对于既往接受过恶性肿瘤治疗的患者,因小肠梗阻而行剖腹手术是否合理?

Is laparotomy for small bowel obstruction justified in patients with previously treated malignancy?

作者信息

Walsh H P, Schofield P F

出版信息

Br J Surg. 1984 Dec;71(12):933-5. doi: 10.1002/bjs.1800711206.

Abstract

We report 53 patients who developed small bowel obstruction some time after the treatment of a primary malignant tumour. Previous treatment of the primary tumour in these patients had been by abdominal surgery (22 patients) or pelvic radiotherapy (20 patients) but 11 of the patients had not received previous abdominal surgery or radiotherapy. All the patients had a laparotomy in an attempt to relieve the obstruction. Seventeen patients had a cause for the obstruction other than secondary malignancy. This was noted particularly when the patients had had pelvic radiotherapy, when radiation change of the ileum causing obstruction was common. Thirty-six patients had obstruction due to secondary tumour and it was found possible to overcome the obstruction in all but two of these. The operative mortality in the patients with secondary malignancy was 19 per cent, but 15 patients (42 per cent) survived for more than a year and the median survival was 11 months. It is concluded that a policy of aggressive surgical intervention is desirable in patients who develop small bowel obstruction after previous treatment for malignant disease.

摘要

我们报告了53例在原发性恶性肿瘤治疗后的一段时间内发生小肠梗阻的患者。这些患者之前对原发性肿瘤的治疗方式为腹部手术(22例)或盆腔放疗(20例),但有11例患者此前未接受过腹部手术或放疗。所有患者均接受了剖腹手术以试图缓解梗阻。17例患者的梗阻原因并非继发性恶性肿瘤。这在患者接受盆腔放疗时尤为明显,此时因回肠放射性改变导致梗阻很常见。36例患者的梗阻是由继发性肿瘤引起的,除其中2例患者外,其余患者的梗阻均得以解除。继发性恶性肿瘤患者的手术死亡率为19%,但有15例患者(42%)存活超过一年,中位生存期为11个月。结论是,对于先前接受恶性疾病治疗后发生小肠梗阻的患者,积极的手术干预策略是可取的。

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