Joubert J, Joubert P H, van der Spuy M, van Graan E
J Toxicol Clin Toxicol. 1984;22(2):187-91. doi: 10.3109/15563658408992554.
Although it is known that extrapyramidal function is dependent upon a balance between cholinergic and dopaminergic effects, only anti-dopaminergic substances commonly induce extrapyramidal symptoms. This paper describes a patient who ingested chlorpyrifos and presented with choreo-athetosis and depressed cholinesterases. She responded to atropine therapy and made a complete recovery. Although not often described excessive cholinergic activity may also produce extrapyramidal symptoms.
虽然已知锥体外系功能依赖于胆碱能和多巴胺能效应之间的平衡，但通常只有抗多巴胺能物质会诱发锥体外系症状。本文描述了一名摄入毒死蜱并出现舞蹈手足徐动症和胆碱酯酶降低的患者。她对阿托品治疗有反应并完全康复。虽然不常被描述，但胆碱能活性过高也可能产生锥体外系症状。
