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[大脑视觉区域个体发育的定量研究]

[Quantitative aspects of the ontogenic development of the visual regions of the brain].

作者信息

Zilles K

出版信息

Fortschr Med. 1978 Jan 12;96(2):63-7.

PMID:620964
Abstract

Quantitative light-microscopic studies on the ontogenetic development of 11 visual brain regions of Tupaia belangeri were done. The fresh volumes of the visual brain regions showed a heterochronical and heterotypical development. Brain regions with overshooting or monotonously increasing growth could be found using computer calculations of logistic curves. Studies on the development of the number of nerve cells and glial cells showed an overshooting growth of the nerve cell quantity and a monotonously increasing growth of the glial cell quantity in the nuclei nn. oculomotorii et trochlearis. A compartment analysis with computer aided stereological procedures was done for the nucl. n. oculomotorii. The present findings as well as those from proceeding investigations serve as the basis for a hypothesis describing the significance of the growth curve for fresh volumes, and especially for the spontaneous degeneration of neurons in the formal genesis of the nervous system.

摘要

对树鼩11个视觉脑区的个体发育进行了定量光镜研究。视觉脑区的新鲜体积呈现出异时性和异型性发育。通过逻辑曲线的计算机计算,可以发现脑区存在过度生长或单调增长的情况。对神经细胞和神经胶质细胞数量发育的研究表明,动眼神经核和滑车神经核中神经细胞数量过度生长,神经胶质细胞数量单调增长。对动眼神经核进行了计算机辅助立体学程序的分区分析。目前的研究结果以及先前研究的结果为一个假设提供了基础,该假设描述了新鲜体积生长曲线的意义,特别是在神经系统形态发生过程中神经元的自发退化。

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