Evaluation of cutaneous amyloid employing anti-keratin antibodies and the immunoperoxidase technique (PAP method).

Thirty-one cases of primary cutaneous amyloidosis were studied by the immunoperoxidase technique (PAP method) employing anti-keratin antibodies. All specimens were examined using consecutive paraffin sections to confirm the correspondence between amyloid existing area and reactive sites. All of the sections examined were non-reactive in amyloid deposited sites whereas the epidermis always showed strong reaction with anti-keratin antibodies.