Huben R P, Schellhammer P F
J Urol. 1982 Sep;128(3):510-2. doi: 10.1016/s0022-5347(17)53021-9.
The records of 100 patients with localized prostatic cancer were examined retrospectively in an effort to determine the usefulness of routine 99mtechnetium bone scans following definitive therapy with 125iodine implantation or external beam irradiation. With a mean followup of 47 months per patient 19 per cent of these patients had positive scans and an additional 15 per cent had scans that were considered equivocal. Of the 100 patients none had a positive scan in the absence of either an elevated serum acid phosphatase or bone pain. In our series the low incidence of positive scans as the sole evidence of disease progression does not support its routine use after definitive therapy for localized carcinoma of the prostate.
对100例局限性前列腺癌患者的记录进行了回顾性检查,以确定在接受¹²⁵碘植入或外照射根治性治疗后进行常规⁹⁹ᵐ锝骨扫描的实用性。每位患者的平均随访时间为47个月,其中19%的患者扫描结果为阳性,另有15%的患者扫描结果被认为不明确。在这100例患者中,没有一例在血清酸性磷酸酶未升高或无骨痛的情况下扫描结果为阳性。在我们的系列研究中,作为疾病进展唯一证据的阳性扫描发生率较低,这并不支持在前列腺局限性癌根治性治疗后常规使用骨扫描。