右旋芬氟拉明和去甲右旋芬氟拉明通过作用于大鼠大脑中不同的5-羟色胺机制来减少食物摄入量。 - Suppr

Suppr

超能文献

D-Fenfluramine and D-norfenfluramine reduce food intake by acting on different serotonin mechanisms in the rat brain.

作者信息

Borsini F, Bendotti C, Aleotti A, Samanin R, Garattini S

出版信息

Pharmacol Res Commun. 1982 Jul;14(7):671-8. doi: 10.1016/s0031-6989(82)80025-8.

DOI:10.1016/s0031-6989(82)80025-8

PMID:6215652

Abstract

摘要

相似文献

D-Fenfluramine and D-norfenfluramine reduce food intake by acting on different serotonin mechanisms in the rat brain.右旋芬氟拉明和去甲右旋芬氟拉明通过作用于大鼠大脑中不同的5-羟色胺机制来减少食物摄入量。

Pharmacol Res Commun. 1982 Jul;14(7):671-8. doi: 10.1016/s0031-6989(82)80025-8.

d-Fenfluramine and salbutamol: two drugs causing anorexia through different neurochemical mechanisms.右旋芬氟拉明和沙丁胺醇：两种通过不同神经化学机制导致厌食的药物。

Int J Obes. 1984;8 Suppl 1:151-7.

Is receptor activation involved in the mechanism by which (+)-fenfluramine and (+)-norfenfluramine deplete 5-hydroxytryptamine in the rat brain?（+）-芬氟拉明和（+）-去甲芬氟拉明使大鼠脑内5-羟色胺耗竭的机制涉及受体激活吗？

Br J Pharmacol. 1982 Mar;75(3):525-30. doi: 10.1111/j.1476-5381.1982.tb09169.x.

Differences between d-fenfluramine and d-norfenfluramine in serotonin presynaptic mechanisms.

J Neurochem. 1983 Mar;40(3):891-3. doi: 10.1111/j.1471-4159.1983.tb08065.x.

Effects of serotonin antagonists on the performance of a simple food acquisition task in rats treated with fenfluramine isomers.血清素拮抗剂对用芬氟拉明异构体处理的大鼠执行简单食物获取任务的影响。

Pharmacol Res Commun. 1985 Dec;17(12):1129-39. doi: 10.1016/0031-6989(85)90025-6.

Fenfluramine and 5-hydroxytryptamine. Part 2: Involvement of brain 5-hydroxytryptamine in the anorectic activity of fenfluramine.芬氟拉明与5-羟色胺。第2部分：脑5-羟色胺在芬氟拉明厌食活性中的作用。

Arzneimittelforschung. 1975 Nov;25(11):1758-62.

Studies on the role of 5-HT receptors in satiation and the effect of d-fenfluramine in the runway test.5-羟色胺受体在饱腹感中的作用及右旋芬氟拉明在跑道试验中的效果研究。

Eur J Pharmacol. 1990 Nov 6;190(1-2):105-12. doi: 10.1016/0014-2999(90)94117-g.

Evidence that hypophagia induced by d-fenfluramine and d-norfenfluramine in the rat is mediated by 5-HT2C receptors.右旋芬氟拉明和去甲右旋芬氟拉明在大鼠中诱导的摄食减少是由5-羟色胺2C受体介导的证据。

Neuropharmacology. 2001 Aug;41(2):200-9. doi: 10.1016/s0028-3908(01)00063-6.

Effect of fenfluramine and norfenfluramine stereoisomers on stimulant effects of d-amphetamine and apomorphine in the rat.芬氟拉明和去甲芬氟拉明立体异构体对大鼠中右旋苯丙胺和阿扑吗啡兴奋作用的影响。

Pharmacol Res Commun. 1980 Jun;12(6):567-74. doi: 10.1016/s0031-6989(80)80142-1.

d-Fenfluramine and d-norfenfluramine hypophagias do not require increased hypothalamic 5-hydroxytryptamine release.右旋芬氟拉明和去甲右旋芬氟拉明引起的食欲减退并不需要增加下丘脑5-羟色胺的释放。

Eur J Pharmacol. 1994 Oct 13;264(1):111-5. doi: 10.1016/0014-2999(94)90646-7.

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J Exp Anal Behav. 2004 Nov;82(3):275-92. doi: 10.1901/jeab.2004.82-275.

Ritanserin attenuates anorectic, endocrine and thermic responses to d-fenfluramine in human volunteers.

Psychopharmacology (Berl). 1993;112(4):461-6. doi: 10.1007/BF02244895.

Role of serotonin receptors in the effect of sertraline on feeding behaviour.血清素受体在舍曲林对进食行为影响中的作用。

Psychopharmacology (Berl). 1993;110(1-2):203-8. doi: 10.1007/BF02246974.

Anorectic effect of fenfluramine isomers and metabolites: relationship between brain levels and in vitro potencies on serotonergic mechanisms.芬氟拉明异构体和代谢物的厌食作用：脑内水平与对血清素能机制的体外效力之间的关系。

Psychopharmacology (Berl). 1985;85(1):111-4. doi: 10.1007/BF00427333.

Fawn hooded rats are subsensitive to the food intake suppressant effects of 5-HT agonists.黄褐带帽大鼠对5-羟色胺激动剂的食物摄入抑制作用反应不敏感。

Psychopharmacology (Berl). 1988;94(4):558-62. doi: 10.1007/BF00212855.

Evidence that d-fenfluramine anorexia is mediated by 5-HT1 receptors.右旋芬氟拉明所致厌食由5-羟色胺1型受体介导的证据。

Psychopharmacology (Berl). 1989;97(2):213-8. doi: 10.1007/BF00442252.

Dexfenfluramine. Its place in weight control.右旋芬氟拉明。其在体重控制中的地位。

Drugs. 1990;39 Suppl 3:53-62. doi: 10.2165/00003495-199000393-00007.

Effect of fenfluramine on prolactin and thyroid-stimulating-hormone response to thyrotropin-releasing-hormone in obese and normal women.芬氟拉明对肥胖和正常女性催乳素及促甲状腺激素对促甲状腺激素释放激素反应的影响。

Eur J Clin Pharmacol. 1990;39(1):13-6. doi: 10.1007/BF02657049.

Dexfenfluramine. A review of its pharmacological properties and therapeutic potential in obesity.右芬氟拉明。其药理学特性及在肥胖症治疗潜力的综述。

Drugs. 1992 May;43(5):713-33. doi: 10.2165/00003495-199243050-00007.

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