Maenhaut-Michel G, Caillet-Fauquet P
Mol Gen Genet. 1982;188(1):143-8. doi: 10.1007/BF00333009.
The survival of UV-irradiated lambda phages is increased when host bacteria are grown in the presence of the base analogue 2-aminopurine (2AP) before infection. This increase in survival, which we have called "2AP-reactivation" depends upon the concentration of 2AP and the time of exposure to 2AP. 2AP-reactivation can be distinguished from Weigle-reactivation in that it is not accompanied by an increase in mutagenesis, does not act on the single-stranded DNA bacteriophage phi X174, and occurs in recA and lexA bacteria. 2AP reactivation does not appear to involve known systems of recombinational repair, as it occurs in recB and recF bacteria, or excision repair, as it occurs in uvrA and uvrB bacteria. It is however dependent upon DNA polymerase I.
当宿主细菌在感染前于碱基类似物2-氨基嘌呤（2AP）存在的情况下生长时，紫外线照射的λ噬菌体的存活率会提高。这种存活率的提高，我们称之为“2AP复活”，它取决于2AP的浓度和暴露于2AP的时间。2AP复活可与韦格尔复活区分开来，因为它不会伴随着诱变率的增加，对单链DNA噬菌体φX174不起作用，并且发生在recA和lexA细菌中。2AP复活似乎不涉及已知的重组修复系统，因为它发生在recB和recF细菌中，也不涉及切除修复，因为它发生在uvrA和uvrB细菌中。然而，它依赖于DNA聚合酶I。
