噬菌体T4中32、41、44、45和62基因的琥珀突变抑制型的诱变和抗诱变表型
Mutator and antimutator phenotypes of suppressed amber mutants in genes 32, 41, 44, 45, and 62 in bacteriophage T4.
作者信息
Watanabe S M, Goodman M F
出版信息
J Virol. 1978 Jan;25(1):73-7. doi: 10.1128/JVI.25.1.73-77.1978.
Abstract
Bacteriophage T4 genes 32, 41, 44, 45, 56, and 62 are essential to DNA replication. Amber mutants (suppressed by su+1, su+2, or su+3 bacteria) in these genes were examined for any mutator or antimutator effects on the reversion of a transition mutation. In every case except for mutations in gene 56, elevated or lowered error frequencies were observed. These results indicate the importance of all of the replicative proteins in the determination of error frequency.
摘要
噬菌体T4的基因32、41、44、45、56和62对DNA复制至关重要。对这些基因中的琥珀突变体（由su+1、su+2或su+3细菌抑制）进行了检测，以观察其对转换突变回复的任何诱变或抗诱变作用。除基因56中的突变外，在每种情况下均观察到错误频率升高或降低。这些结果表明所有复制蛋白在错误频率测定中的重要性。
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