Van Geffel R, Hubert E, Urbain J
Immunol Lett. 1982 Sep;5(3):155-9. doi: 10.1016/0165-2478(82)90101-8.
The ratio between inducer and cytotoxic/suppressor subset T-cells was studied in 11 cystic fibrosis patients and 11 non-cystic fibrosis controls. No statistically significant difference was found between the two groups. It is suggested that the major immune deficiency in some patients suffering from cystic fibrosis is a state of tolerance to the same bacterial antigens such as Pseudomonas aeruginosa. Inhibitory factors are present in the serum of the most affected patients.
在11名囊性纤维化患者和11名非囊性纤维化对照者中研究了诱导性T细胞与细胞毒性/抑制性T细胞亚群之间的比例。两组之间未发现统计学上的显著差异。有人提出，一些囊性纤维化患者的主要免疫缺陷是对诸如铜绿假单胞菌等相同细菌抗原的耐受状态。在受影响最严重的患者血清中存在抑制因子。
