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迟发性溶血性输血反应。一个常被漏诊的情况。

Delayed hemolytic transfusion reactions. An often-missed entity.

作者信息

Solanki D, McCurdy P R

出版信息

JAMA. 1978 Feb 20;239(8):729-31.

PMID:621892
Abstract

Delayed hemolytic transfusion reactions in eight persons were manifested solely or primarily by an apparently unexplained posttransfusion decrease in the hematocrit value. Alloantibodies were eventually found in all eight patients, but were sometimes undetectable for as long as 72 hours after the reaction. This did not preclude the occurrence of a new, acute hemolytic reaction. There were three instances of reversible renal failure complicating the reaction. In two patients, some or all of the antibodies became undetectable after four and nine months. In a third, the indirect antiglobulin reactions became considerably weaker after 12 months. Patients previously sensitized to RBC antigens should have available records inspected and a warning device (wristband or wallet card) provided to help prevent reactions caused by an anamnestic antibody rise.

摘要

8名患者发生的迟发性溶血性输血反应仅以或主要以输血后血细胞比容值明显不明原因下降为表现。所有8例患者最终均发现了同种抗体,但有时在反应后长达72小时内无法检测到。这并不排除发生新的急性溶血反应。有3例反应并发可逆性肾衰竭。2例患者在4个月和9个月后部分或全部抗体无法检测到。第3例患者在12个月后间接抗球蛋白反应明显减弱。既往对红细胞抗原致敏的患者应检查现有记录,并提供警示装置(腕带或钱包卡),以帮助预防由回忆性抗体升高引起的反应。

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Delayed hemolytic transfusion reactions. An often-missed entity.迟发性溶血性输血反应。一个常被漏诊的情况。
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Delayed hemolytic transfusion reactions.迟发性溶血性输血反应
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Delayed haemolytic transfusion reactions in patients with sickle cell disease.镰状细胞病患者的迟发性溶血性输血反应。
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