Jacobs L B, Shirey R S, Ness P M
Department of Pathology, Johns Hopkins Hospital, Baltimore, MD 21287-6667, USA.
Arch Pathol Lab Med. 1996 Jul;120(7):684-6.
Hemolysis due to donor-derived antibodies produced by "passenger" B lymphocytes, called passenger lymphocyte syndrome, has been described in ABO-unmatched solid organ and bone marrow transplant recipients. Delayed hemolytic transfusion reactions occur within a similar time frame and have similar clinical and serologic findings. To our knowledge, we report the first case of hemolysis due to the simultaneous occurrence of passenger lymphocyte syndrome (donor-derived anti-A) and a delayed hemolytic transfusion reaction (recipient-produced anti-E) in a liver transplant patient.
由“过客”B淋巴细胞产生的供体源性抗体导致的溶血，即过客淋巴细胞综合征，已在ABO血型不匹配的实体器官和骨髓移植受者中有所描述。迟发性溶血性输血反应在类似的时间范围内发生，且具有相似的临床和血清学表现。据我们所知，我们报告了首例肝移植患者同时发生过客淋巴细胞综合征（供体源性抗A）和迟发性溶血性输血反应（受者产生的抗E）导致溶血的病例。
