Lindegård B
J Affect Disord. 1982 Dec;4(4):383-93. doi: 10.1016/0165-0327(82)90034-9.
The entire middle-aged male urban population of a Swedish city, as defined by a census in November 1969, was assessed for any mental hospital hospitalization during a 3-year period (1978-1980), as well as for any general hospital hospitalization during a 10-year period (1970-1979) within the catchment area. Inpatients of the mental hospital population belonging to the cohort and put in the categories 'Psychiatric alcoholic spectrum' and 'Severe depression' were studied for diagnoses of physical illness during any general hospital hospitalization. The psychiatric alcoholic spectrum was associated positively with infections, injuries, alcohol intoxication, pancreatitis, liver cirrhosis, arthritis/rheumatic diseases and duodenal peptic ulcer; and negatively with malignant neoplasms, myocardial infarction, gallstone disease and urolithiasis. Severe depression was associated positively with infections, myocardial infarction, asthma and alcohol intoxication. A nosologic taxonomy, aimed at explaining the epidemiological associations recorded, is suggested.
以1969年11月的人口普查所定义的瑞典某城市全体中年男性城市人口,在3年期间(1978 - 1980年)接受了精神病院住院情况评估,以及在10年期间(1970 - 1979年)在该集水区范围内接受了综合医院住院情况评估。对该队列中属于“精神病性酒精谱系”和“重度抑郁”类别的精神病院住院患者,研究其在任何综合医院住院期间的躯体疾病诊断情况。精神病性酒精谱系与感染、损伤、酒精中毒、胰腺炎、肝硬化、关节炎/风湿性疾病和十二指肠消化性溃疡呈正相关;与恶性肿瘤、心肌梗死、胆结石病和尿路结石呈负相关。重度抑郁与感染、心肌梗死、哮喘和酒精中毒呈正相关。本文提出了一种旨在解释所记录的流行病学关联的疾病分类法。