Marchevsky A M, Kaneko M
Hum Pathol. 1983 Jan;14(1):86-8. doi: 10.1016/s0046-8177(83)80051-3.
A 49-year-old woman had an unusual sarcoma that recurred three times in four years. The tumor manifested initially as a subcutaneous abdominal wall nodule composed of lymphohistiocytic malignant lymphoma and spindle cell sarcoma with epithelioid and clear cell elements. The neoplasm recurred first as a spindle cell sarcoma in the lumbar area, second as a malignant lymphoma in the subcutaneous tissue of the right shoulder, and third as a spindle cell sarcoma with lymphohistiocytic areas in the abdominal wall. Ultrastructural studies of this last tumor nodule demonstrated the unequivocal smooth muscle features of the spindle cells. Histogenetic implications of this neoplasm are discussed. It is proposed that the tumor represents an unusual variant of malignant mesenchymoma of soft tissues.
一名49岁女性患有一种罕见的肉瘤，该肉瘤在四年内复发了三次。肿瘤最初表现为腹壁皮下结节，由淋巴组织细胞性恶性淋巴瘤和具有上皮样及透明细胞成分的梭形细胞肉瘤组成。肿瘤首次复发为腰部的梭形细胞肉瘤，第二次复发为右肩部皮下组织的恶性淋巴瘤，第三次复发为腹壁含有淋巴组织细胞区域的梭形细胞肉瘤。对最后一个肿瘤结节的超微结构研究明确显示了梭形细胞的平滑肌特征。本文讨论了该肿瘤的组织发生学意义。提出该肿瘤代表软组织恶性间叶瘤的一种罕见变体。
