Lin J Y, Tsai R Y
Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Dermatol Surg. 1999 Jun;25(6):489-91. doi: 10.1046/j.1524-4725.1999.08290.x.
Cutaneous leiomyosarcoma is a rare soft tissue sarcoma with a predilection for the lower extremities. Leiomyosarcoma of the face is very rare. Subcutaneous leiomyosarcoma has a higher likelihood of recurrence and metastases than that of the superficial dermal type.
The dermatologic surgeon and pathologist should be familiar with the characters of subcutaneous leiomyosarcoma.
We report a case of subcutaneous leiomyosarcoma on the face with the results of histologic examination and immunohistochemical studies.
Leiomyosarcoma of the face is exceedingly rare. The deep subcutaneous type is thought to arise from the smooth muscle of the vascular wall. The neoplasm we report here has deep tumor invasion, high malignancy grade (3B), and large tumor size. Wide excision and postoperative radiotherapy were performed.
Subcutaneous leiomyosarcoma has a higher likelihood of recurrence and metastases than that of the superficial dermal type. The most effective treatment is wide excision with 3-5 cm lateral margins and a depth that includes subcutaneous tissue and fascia.
皮肤平滑肌肉瘤是一种罕见的软组织肉瘤，好发于下肢。面部平滑肌肉瘤极为罕见。皮下平滑肌肉瘤比浅表真皮型更易复发和转移。
皮肤科外科医生和病理学家应熟悉皮下平滑肌肉瘤的特征。
我们报告一例面部皮下平滑肌肉瘤病例，并给出组织学检查和免疫组化研究结果。
面部平滑肌肉瘤极其罕见。深部皮下型被认为起源于血管壁的平滑肌。我们在此报告的肿瘤具有深部肿瘤浸润、高恶性分级（3B 级）和较大肿瘤尺寸。进行了广泛切除和术后放疗。
皮下平滑肌肉瘤比浅表真皮型更易复发和转移。最有效的治疗方法是进行广泛切除，切缘外侧 3 - 5 厘米，深度包括皮下组织和筋膜。
