Sengupta J, Paria B C, Manchanda S K
J Reprod Fertil. 1983 Mar;67(2):369-72. doi: 10.1530/jrf.0.0670369.
Preimplantation embryo development was arrested at the premorula stage in hamsters ovariectomized on Day 1 of pregnancy. This effect was reversed when 500 micrograms progesterone were administered daily. Oestradiol-17 beta given alone had no significant effect on the cleavage rate or blastocyst formation, but a synergistic response was evident when a suboptimal (30 micrograms) dose of progesterone was given with 50 ng oestradiol-17 beta. Cholesterol and hydrocortisol had no effect on embryo development.
在妊娠第1天切除卵巢的仓鼠中，植入前胚胎发育在桑葚胚前期停滞。每天给予500微克孕酮可逆转这种效应。单独给予雌二醇-17β对卵裂率或囊胚形成没有显著影响，但当给予次优剂量（30微克）的孕酮与50纳克雌二醇-17β时，协同反应明显。胆固醇和氢化可的松对胚胎发育没有影响。
