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[使用123I-马尿酸进行肾放射性同位素研究以监测移植手术]

[Renal radioisotope study with 123I-hippuran in the monitoring of transplants].

作者信息

Champailler A, Juge J, Herrmann T, Berthoux F, Healy J C

出版信息

Presse Med. 1983 Jan 8;12(1):31-5.

PMID:6220271
Abstract

Hippuran labelled with iodine 123 is now used for short- and long-term monitoring of renal transplants. Sixty-one explorations were performed in 24 patients, using this new radiopharmaceutical agent. Repeated explorations, facilitated by the lower doses of radiations as compared with 131I-hippuran, are particularly useful to diagnose thrombosis of the renal artery, early acute tubular lesions, acute and chronic rejection and impaired evacuation of the kidney. 123I-hippuran is the first-choice method of exploration of transplanted kidneys and can be followed, if required, by explorations more aggressive for the patient and the kidney.

摘要

用碘123标记的马尿酸钠现用于肾移植的短期和长期监测。使用这种新型放射性药物对24例患者进行了61次检查。与131I-马尿酸钠相比,较低剂量的辐射便于进行重复检查,这对于诊断肾动脉血栓形成、早期急性肾小管病变、急慢性排斥反应以及肾脏排泄功能受损特别有用。123I-马尿酸钠是移植肾检查的首选方法,如果需要,随后可采用对患者和肾脏更具侵入性的检查。

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