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[萎缩性带状痣]

[Atrophic zoniform nevus].

作者信息

Guzzeloni E, Manfredi G, Zampetti M, De Panfilis G, Allegra F

出版信息

Acta Biomed Ateneo Parmense. 1982;53(5):341-6.

PMID:6220545
Abstract

The first, in our knowledge, case of naevus atrophicus zoniforme in italian literature is here reported. A 13 year old girl had a thirteen years history of involved numerous depressed areas of skin of the right anterior region of the chest and of the right upper arm. The lesions were round, grey-bluish, smooth, depressed, completely asymptomatic. No inflammatory changes were noticed in affected patches nor in surrounding normal skin. The histologic changes were compatible with dermal atrophy: epidermis was quite normal; dermis war very thin; the thickness of hypodermis was increased. Some large nervous structures were visible within deep dermis. Histochemical changes mainly involved elastic fibers, whose thickness was considerably increased. The diagnosis of naevus atrophicus zoniforme is discussed, in comparison to other idiopathic atrophies. In conclusion, the main characters of naevus atrophicus zoniforme, according to literature data, are confirmed in our case: 1) congenital appearance 2) zoniforme distribution 3) dermal atrophy 4) thickening of elastic fibers 5) occurrence of large nervous structures in the dermis.

摘要

据我们所知,本文报道了意大利文献中首例带状萎缩性痣病例。一名13岁女孩有长达13年的病史,其右侧胸部前方区域及右上臂皮肤出现多处凹陷性皮损。皮损呈圆形,灰蓝色,表面光滑,凹陷,完全无症状。在受累斑片及周围正常皮肤中均未发现炎症改变。组织学改变符合真皮萎缩:表皮基本正常;真皮非常薄;皮下组织厚度增加。在真皮深层可见一些粗大的神经结构。组织化学改变主要累及弹性纤维,其厚度显著增加。本文将带状萎缩性痣的诊断与其他特发性萎缩进行了讨论。总之,根据文献资料,我们病例中带状萎缩性痣的主要特征得到了证实:1)先天性外观;2)带状分布;3)真皮萎缩;4)弹性纤维增厚;5)真皮中出现粗大神经结构。

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