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膀胱癌中的十种基因多态性。

Ten genetic polymorphisms in bladder cancer.

作者信息

Cartwright R A, Adib R, Appleyard I, Coxon J G, Glashan R W, Richards B, Robinson M R, Sunderland E, Barham-Hall D

出版信息

J Med Genet. 1983 Apr;20(2):112-6. doi: 10.1136/jmg.20.2.112.

Abstract

Data are presented on a group of cases of primary carcinoma of the bladder, detailing red cell surface blood group antigenic phenotypes, serum haptoglobin phenotypes, and some red cell isoenzyme phenotypes. Account is taken of the stage of the disease at presentation. The results are compared with corresponding phenotype frequencies in groups of presumed healthy persons originating either in Yorkshire or County Durham. Differences in relative incidences were found in the haptoglobin, phosphoglucomutase (PGM), and some other systems. These are both differences between all cases and controls and between particular stages at presentation and controls.

摘要

本文呈现了一组膀胱癌原发性病例的数据,详细说明了红细胞表面血型抗原表型、血清触珠蛋白表型以及一些红细胞同工酶表型。同时考虑了疾病初发时的阶段。将这些结果与来自约克郡或达勒姆郡的假定健康人群组中的相应表型频率进行了比较。在触珠蛋白、磷酸葡萄糖变位酶(PGM)和其他一些系统中发现了相对发病率的差异。这些差异既存在于所有病例与对照组之间,也存在于初发时的特定阶段与对照组之间。

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