脂调素：糖皮质激素作用的一种可能介质。
Lipomodulin: a possible mediator of the action of glucocorticoids.
作者信息
Hirata F
出版信息
Adv Prostaglandin Thromboxane Leukot Res. 1983;11:73-8.
PMID:6221579
Abstract
Lipomodulin, a protein with a MW of 40,000, is induced in many cells by glucocorticoids. This protein can mimic a variety of biological activities of glucocorticoids such as anti-inflammation, immunosuppression, and promotion of cellular differentiation. Since anti-lipomodulin antibody can block these effects of both glucocorticoids and lipomodulin, it is quite possible that lipomodulin is a mediator of glucocorticoids.
摘要
脂调素是一种分子量为40000的蛋白质，在许多细胞中由糖皮质激素诱导产生。这种蛋白质可以模拟糖皮质激素的多种生物学活性，如抗炎、免疫抑制和促进细胞分化。由于抗脂调素抗体可以阻断糖皮质激素和脂调素的这些作用，因此脂调素很可能是糖皮质激素的一种介质。
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