脂皮质素（脂调素）的分离与特性研究
Isolation and characterization of lipocortin (lipomodulin).
作者信息
Hirata F, Notsu Y, Yamada R, Ishihara Y, Wano Y, Kunos I, Kunos G
出版信息
Agents Actions. 1986 Jan;17(3-4):263-6. doi: 10.1007/BF01982617.
PMID:3962767
Abstract
Lipocortin is a phospholipase inhibitory protein whose synthesis is induced in various cells by glucocorticoids. At least three species with molecular weights of 40,000, 30,000, and 15,000 are presently known. This protein mimics the anti-inflammatory action of glucocorticoids in vitro as well as in vivo. The synthesis of the protein appears to be associated with the MHC genes.
摘要
脂皮质素是一种磷脂酶抑制蛋白，其合成由糖皮质激素在多种细胞中诱导产生。目前已知至少有三种分子量分别为40000、30000和15000的物种。这种蛋白质在体外和体内都能模拟糖皮质激素的抗炎作用。该蛋白质的合成似乎与主要组织相容性复合体（MHC）基因有关。
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