Marcandoro J, Sobel A
Presse Med. 1983 May 28;12(23):1483-7.
A retrospective study of 258 reports of Goodpasture's syndrome published from 1955 to 1982 has made it possible to follow changes in prognosis and to determine the present prognostic factors. In these 27 years, the mortality rate has dropped from 86% to 13%, and 51% of the patients now survive without dialysis. Death from respiratory failure virtually disappeared as soon as plasmapheresis was introduced. However 36% of patients are still threatened with chronic renal failure, the risk being higher in patients with initial oliguria or anuria and with extra-capillary crescents involving more than 50% of glomerules, and still higher when these two factors coexist. In such a case, only 21% of patients may hope to survive in renal autonomy.
一项对1955年至1982年间发表的258例Goodpasture综合征报告的回顾性研究，使得追踪预后变化并确定当前的预后因素成为可能。在这27年中，死亡率已从86%降至13%，现在51%的患者在无需透析的情况下存活。一旦引入血浆置换，死于呼吸衰竭的情况几乎立即消失。然而，36%的患者仍面临慢性肾衰竭的威胁，初始少尿或无尿以及超过50%的肾小球出现毛细血管外新月体的患者风险更高，当这两个因素同时存在时风险更高。在这种情况下，只有21%的患者有望自主肾功能存活。
