Planas A T, Zamkoff K W, Poiesz B J, Kurec A S, Davey F R
Ann Clin Lab Sci. 1983 May-Jun;13(3):193-200.
A diagnosis of prolymphocytic leukemia was made from the blood and bone marrow of a 50 year old man. The neoplastic cells were studied by use of light and electron microscopy. Neoplastic cells were focally positive for acid phosphatase and alpha naphthyl acetate esterase. In addition, neoplastic cells formed rosettes with sheep erythrocytes and reacted with Leu-1 and Leu-2a but not Leu-3a antisera. No terminal deoxynucleotidyl transferase (TdT) activity was noted in these cells. It is concluded that these neoplastic cells were phenotypically mature suppressor T lymphocytes. Furthermore, T and B cell prolymphocytic leukemias were compared according to clinico-pathological, cytochemical, ultrastructural, and immunological findings derived from our review of the current literature.
对一名50岁男性的血液和骨髓进行检查后，确诊为幼淋巴细胞白血病。利用光学显微镜和电子显微镜对肿瘤细胞进行了研究。肿瘤细胞酸性磷酸酶和α萘乙酸酯酶呈局灶性阳性。此外，肿瘤细胞与绵羊红细胞形成玫瑰花结，并与抗Leu-1和抗Leu-2a血清反应，但不与抗Leu-3a血清反应。这些细胞未检测到末端脱氧核苷酸转移酶（TdT）活性。结论是这些肿瘤细胞在表型上为成熟的抑制性T淋巴细胞。此外，根据我们对当前文献的综述得出的临床病理、细胞化学、超微结构和免疫学结果，对T细胞和B细胞幼淋巴细胞白血病进行了比较。
