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寻常痤疮患者的淋巴细胞亚群

Lymphocyte subpopulations in patients with acne vulgaris.

作者信息

Holland D B, Gowland G, Cunliffe W J

出版信息

Br J Dermatol. 1983 Aug;109(2):199-203. doi: 10.1111/j.1365-2133.1983.tb07081.x.

DOI:10.1111/j.1365-2133.1983.tb07081.x
PMID:6223653
Abstract

T- and B-lymphocyte subpopulations were measured in the peripheral blood of patients with varying severity of acne and in acne-free control subjects. Increased severity of acne correlated with an increased number of T lymphocytes, helper T cells and B cells, while the number of suppressor T cells remained normal and did not alter significantly. This evidence suggests that there is no lack of regulation of the immune response in acne patients.

摘要

在不同严重程度痤疮患者及无痤疮对照者的外周血中检测了T淋巴细胞和B淋巴细胞亚群。痤疮严重程度增加与T淋巴细胞、辅助性T细胞和B细胞数量增加相关,而抑制性T细胞数量保持正常且无显著变化。这一证据表明痤疮患者不存在免疫反应调节缺陷。

相似文献

1
Lymphocyte subpopulations in patients with acne vulgaris.寻常痤疮患者的淋巴细胞亚群
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Investigating the Impact of Circulating Immune Cells on Acne Using Mendelian Randomization.利用孟德尔随机化研究循环免疫细胞对痤疮的影响。
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2
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转录组学分析表明,维甲酸可逆转痤疮相关基因表达变化。
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