Lum L G, Benveniste E, Steinberg A D, Waldmann T A, Blaese R M
Cell Immunol. 1983 Aug;80(1):105-14. doi: 10.1016/0008-8749(83)90098-9.
Patients with various immunodeficiency and autoimmune disorders were examined for the proportions of T cells bearing Fc-IgA, Fc-IgG, and Fc-IgM receptors. These disorders included common variable immunodeficiency, systemic lupus erythematosus, ataxia-telangiectasia, selective IgA deficiency, and the Wiskott-Aldrich syndrome. Abnormal proportions (higher or lower than an interval containing 95% of our normal values) of Fc-IgA receptor-bearing T cells (TA) were found in common variable immunodeficiency, systemic lupus erythematous, ataxia-telangiectasia, and selective IgA deficiency. However, the proportion of T cells bearing Fc receptors did not correlate with their functional activity in in vitro immunoglobulin production assays.
对患有各种免疫缺陷和自身免疫性疾病的患者进行了检测，以确定携带Fc-IgA、Fc-IgG和Fc-IgM受体的T细胞比例。这些疾病包括常见变异型免疫缺陷、系统性红斑狼疮、共济失调毛细血管扩张症、选择性IgA缺乏症和威斯科特-奥尔德里奇综合征。在常见变异型免疫缺陷、系统性红斑狼疮、共济失调毛细血管扩张症和选择性IgA缺乏症中，发现携带Fc-IgA受体的T细胞（TA）比例异常（高于或低于包含我们95%正常值的区间）。然而，在体外免疫球蛋白产生试验中，携带Fc受体的T细胞比例与其功能活性并无相关性。
