White I R, Stewart J R, Rycroft R J
Contact Dermatitis. 1983 Jul;9(4):300-3. doi: 10.1111/j.1600-0536.1983.tb04395.x.
Organic di-isocyanates are used widely in industry. The concomitant respiratory complications are well-known. Cutaneous problems precipitated by skin contact with these chemicals are less well recognised. Allergic contact dermatitis caused by exposure to di-cyclohexylmethane 4,4'-di-isocyanate has been demonstrated in a factory where it was used to form a surface-coating polyurethane. Attention to hygiene methods may have reduced the incidence of cases.