de Guembecker C, de Guembecker W, Delforge P M, Duriez R
Rev Chir Orthop Reparatrice Appar Mot. 1983;69(4):317-21.
Sixty-one cases of osteogenesis imperfecta were studied to try to discover the cause of metaphyseal and epiphyseal deformities. These deformities were noticeable in 8 cases out of 61 at the level of the upper and lower end of the femur in all cases and sometimes at the level of the lower end of the tibia and the upper end of the humerus. Several grades are described: First grade - protrusion of the growth plate into the epiphysis. Second grade - disorganization of the architecture of the epiphysis. Third grade - major deformity. It seems that the deformities are secondary to lesions of the growth plates. Several hypotheses are suggested. The authors consider that the main role is played by segmental fractures creating areas of ischemia in the epiphyses.
对61例成骨不全症患者进行了研究,以试图找出干骺端和骨骺畸形的原因。在61例患者中,有8例在股骨上下端均出现了明显的畸形,有时在胫骨下端和肱骨上端也有畸形。文中描述了几个等级:一级——生长板向骨骺突出;二级——骨骺结构紊乱;三级——严重畸形。这些畸形似乎是生长板损伤的继发结果。文中提出了几种假设。作者认为主要原因是节段性骨折导致骨骺出现缺血区域。