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[长期运动减少对大鼠生长及骨骼肌的影响]

[Effect of prolonged hypokinesia on the growth and skeletal musculature in the rat].

作者信息

Il'ina-Kakueva E I, Savik Z F

出版信息

Arkh Anat Gistol Embriol. 1983 Aug;85(8):27-33.

PMID:6227310
Abstract

Hypokinesia lasting for 1-5.5 months does not produce any muscular atrophy, but results in ceasing their growth and the growth of the animal. In the muscles, besides the soleus muscle, not any essential structural changes occur. The changes in the soleus muscle are manifested as a focal sclerosis and formation of new muscle fibers. They are considered as a result of a disturbed hemodynamics in it, that occurs during the first days of hypokinesia. During the readaptation period the animals and their muscles begin to grow again. A suggestion is expressed that one of the pathogenic causes making the growth stop is the stress that decreases the somatotrophic function of the hypophysis.

摘要

持续1至5.5个月的运动功能减退不会导致任何肌肉萎缩,但会导致肌肉生长停止以及动物生长停滞。除比目鱼肌外,其他肌肉未出现任何实质性结构变化。比目鱼肌的变化表现为局灶性硬化和新肌纤维形成。这些变化被认为是运动功能减退最初几天比目鱼肌内血液动力学紊乱的结果。在重新适应期,动物及其肌肉开始再次生长。有一种观点认为,导致生长停止的致病原因之一是应激,它会降低垂体的促生长功能。

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