Breslau N
J Abnorm Child Psychol. 1983 Sep;11(3):379-91. doi: 10.1007/BF00914246.
This study examined the appropriateness of siblings as controls in the psychological assessment of children with chronic illness or disability. Findings from 304 cases and 360 randomly selected controls were compared to findings from a subset of 206 case-sibling pairs. Cases were children 6 to 18 years of age with cystic fibrosis, cerebral palsy, myelodysplasia, and multiple handicaps, selected from specialty clinics in two teaching hospitals in the Cleveland area. Results from both data sets were in agreement on major findings indicating that children with cystic fibrosis are not at increased risk for psychopathology, whereas children in the remaining three diagnostic groups show a substantial excess in Mentation Problems and Isolation. The comparisons with matched siblings underestimated pathology in the disabled children in Regressive-Anxiety and aggressive behavior.
本研究探讨了在对患有慢性疾病或残疾儿童进行心理评估时，将兄弟姐妹作为对照的合理性。将304例病例和360名随机选取的对照的结果，与206对病例-兄弟姐妹对子子集的结果进行了比较。病例为6至18岁患有囊性纤维化、脑瘫、脊髓发育不良和多重残疾的儿童，选自克利夫兰地区两家教学医院的专科诊所。两个数据集的结果在主要发现上是一致的——表明患有囊性纤维化的儿童出现精神病理学问题的风险并未增加，而其余三个诊断组的儿童在思维问题和社交孤立方面则显著更多。与匹配的兄弟姐妹进行比较时，低估了残疾儿童在退行性焦虑和攻击行为方面的病理情况。
