Melconian A K, Brun Y, Fleurette J
J Hyg (Lond). 1983 Oct;91(2):235-42. doi: 10.1017/s0022172400060241.
The production of enterotoxins A, B, C and F by strains of Staphylococcus aureus isolated from various clinical sources and from isolates implicated in food poisoning was investigated. One hundred and ninety one of the 374 clinical strains (51.1%) were found to be enterotoxigenic; of these, 81 (27.7%) strains produced enterotoxin A, 57 (15.3%) strains produced enterotoxin B, 23 (6.2%) strains produced enterotoxin C, and 64 (17.1%) strains produced enterotoxin F. These enterotoxigenic strains were most frequently lysed by phages of group III (21.5%) or were not typable (22%). Eighteen of the 29 strains implicated in food poisoning were enterotoxigenic. The correlation of antigens and bacteriophage patterns with enterotoxigenicity was determined: enterotoxin A being related to a4 antigen, enterotoxin B to phages of 94/96 complex with c1, o antigens, and enterotoxin F to phages of group I with 2632, k1k2, m antigens.
对从各种临床来源分离出的金黄色葡萄球菌菌株以及与食物中毒有关的分离株产生肠毒素A、B、C和F的情况进行了研究。在374株临床菌株中,有191株(51.1%)被发现具有产肠毒素能力;其中,81株(27.7%)产生肠毒素A,57株(15.3%)产生肠毒素B,23株(6.2%)产生肠毒素C,64株(17.1%)产生肠毒素F。这些产肠毒素菌株最常被III组噬菌体裂解(21.5%)或无法分型(22%)。在29株与食物中毒有关的菌株中,有18株具有产肠毒素能力。确定了抗原和噬菌体模式与产肠毒素能力的相关性:肠毒素A与a4抗原相关,肠毒素B与94/96复合体的噬菌体以及c1、o抗原相关,肠毒素F与I组噬菌体以及2632、k1k2、m抗原相关。