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[职业噪声暴露工人的脂质、胶原蛋白和黏多糖代谢]

[Lipid, collagen and mucopolysaccharide metabolism in workers exposed to occupational noise].

作者信息

Sroczyński J, Wegiel A, Wieja A, Kuleszyńska G, Mamczar A, Bresler M

出版信息

Med Pr. 1983;34(3):245-9.

PMID:6227790
Abstract

In forty-nine workers of steelworks, exposed to noise of 88-112 dBA level, the concentration of total lipids, phospholipids, lipoproteins beta, total cholesterol, triglycerides and free fatty acids was determined. In addition, in the urine collected at night and urine collected within 8 working hours, the concentration of hydroxyproline (HP) and glycosaminoglycans (GAG) was determined. The studies showed an increase in all test kinds of fats significant for total lipids and phospholipids. This may imply the atheromatogenic effect of noise. On the other hand, no changes have been found in HP and GAG excretion.

摘要

在49名暴露于88 - 112分贝A声级噪音的钢铁厂工人中,测定了总脂质、磷脂、β脂蛋白、总胆固醇、甘油三酯和游离脂肪酸的浓度。此外,还测定了夜间收集的尿液和8小时工作时间内收集的尿液中羟脯氨酸(HP)和糖胺聚糖(GAG)的浓度。研究表明,所有检测的脂肪种类均有增加,总脂质和磷脂增加显著。这可能意味着噪音具有致动脉粥样硬化作用。另一方面,未发现HP和GAG排泄有变化。

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