Sandover J
Spine (Phila Pa 1976). 1983 Sep;8(6):652-8. doi: 10.1097/00007632-198309000-00011.
Although the epidemiologic evidence is not convincing, a number of studies indicate that those exposed to dynamic loads may have increased risk to low-back disorders. A review of the available evidence suggests that chronic low-back pain relates to disc degeneration and that this in turn may be accelerated by mechanical failure in the region of the end-plate and subchondral bone or in the annulus. Two hypotheses are proposed to relate fatigue induced failure of vertebral tissues to disc degeneration. The extent of dynamic stresses on the vertebral motion segment arising from transport are investigated, and the results indicate that fatigue induced failure is a distinct possibility. The implications of these suggestions for environmental health protection are briefly discussed.
尽管流行病学证据并不确凿，但多项研究表明，暴露于动态负荷下的人群患下背部疾病的风险可能会增加。对现有证据的综述表明，慢性下背部疼痛与椎间盘退变有关，而椎间盘退变反过来又可能因终板和软骨下骨区域或纤维环的机械故障而加速。提出了两种假说，将椎体组织的疲劳诱导失效与椎间盘退变联系起来。研究了运输过程中椎体运动节段上动态应力的程度，结果表明疲劳诱导失效是一种明显的可能性。简要讨论了这些建议对环境保护的意义。
